New cryoballoon generation enhances procedural efficacy without compromising safety

Efficacy, High Procedural Safety And Rapid Optimization Of Cryoballoon Atrial Fibrillation Ablation In The Hands Of A New Operator.

BACKGROUND Cryoballoon (CB) ablation is successful in eliminating atrial fibrillation (AF). PURPOSE The purpose of this study was to assess procedural efficacy and safety of CB ablation performed by a newly trained operator. METHODS Forty patients with documented paroxysmal AF (58 ± 11 years, 26 male) undergoing CB catheter ablation were prospectively enrolled. RESULTS Electrical pulmonar...

Clinical inquiries. Which medications can be split without compromising efficacy and safety?

Split tablets of lisinopril are as effective as whole tablets of the same dose for hypertension (strength of recommendation [SOR]: B, based on small randomized crossover study). Similarly, split tablets of atorvastatin, lovastatin, and simvastatin are no less effective for lowering cholesterol (SOR: B, based on retrospective cohort studies). Extended-release, enteric-coated, or tablets that can...

Comparative efficacy and safety of contact force-sensing catheter and second-generation cryoballoon ablation for atrial fibrillation: a meta-analysis

This meta-analysis compared the efficacy and safety of the contact force (CF)-sensing catheter and second-generation cryoballoon (CB) ablation for treating atrial fibrillation (AF). Six controlled clinical trials comparing ablation for AF using a CF-sensing catheter or second-generation CB were identified from PubMed, EMBASE, Cochrane Library, Wanfang Data, and China National Knowledge Infrastr...

Efficient Logging without Compromising Testability

Rhodium nanoparticle catalysts stabilized with a polymer that enhances stability without compromising activity.

Rh NPs coated with a PVP-derived polymer, that combines several distinct protective interactions, exhibit superior thermal and catalytic stability compared to analogue NPs coated with PVP.